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8DB9

Adenosine/guanosine nucleoside hydrolase bound to inhibitor

Summary for 8DB9
Entry DOI10.2210/pdb8db9/pdb
DescriptorInosine-uridine preferring nucleoside hydrolase family protein, CALCIUM ION, 1-beta-D-ribofuranosyl-1H-1,2,4-triazole-3-carboximidamide (3 entities in total)
Functional Keywordsnucleoside, hydrolase, adenosine, guanosine, parasitic, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceTrichomonas vaginalis
Total number of polymer chains4
Total formula weight134795.32
Authors
Muellers, S.N.,Allen, K.N.,Stockman, B.J. (deposition date: 2022-06-14, release date: 2022-09-07, Last modification date: 2024-04-03)
Primary citationMuellers, S.N.,Nyitray, M.M.,Reynarowych, N.,Saljanin, E.,Benzie, A.L.,Schoenfeld, A.R.,Stockman, B.J.,Allen, K.N.
Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase.
Biochemistry, 61:1853-1861, 2022
Cited by
PubMed: 35994320
DOI: 10.1021/acs.biochem.2c00361
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.89 Å)
Structure validation

221051

數據於2024-06-12公開中

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