8DB9

Adenosine/guanosine nucleoside hydrolase bound to inhibitor

8DB9 の概要

• エントリーDOI: 10.2210/pdb8db9/pdb
• 分子名称: Inosine-uridine preferring nucleoside hydrolase family protein, CALCIUM ION, 1-beta-D-ribofuranosyl-1H-1,2,4-triazole-3-carboximidamide (3 entities in total)
• 機能のキーワード: nucleoside, hydrolase, adenosine, guanosine, parasitic, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Trichomonas vaginalis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 134795.32

構造登録者

Muellers, S.N.,Allen, K.N.,Stockman, B.J. (登録日: 2022-06-14, 公開日: 2022-09-07, 最終更新日: 2024-04-03)

• 主引用文献: Muellers, S.N.,Nyitray, M.M.,Reynarowych, N.,Saljanin, E.,Benzie, A.L.,Schoenfeld, A.R.,Stockman, B.J.,Allen, K.N.; Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase.; Biochemistry, 61:1853-1861, 2022; PubMed: 35994320; DOI: 10.1021/acs.biochem.2c00361

実験手法

X-RAY DIFFRACTION (2.89 Å)