8D84

E. faecium MurAA in complex with UDP-N-acetylmuramic acid (UNAM) and a covalent adduct of PEP with Cys119

Summary for 8D84

• Entry DOI: 10.2210/pdb8d84/pdb
• Related: 7TB0
• Descriptor: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid (3 entities in total)
• Functional Keywords: muraa, transferase
• Biological source: Enterococcus faecalis
• Total number of polymer chains: 12
• Total formula weight: 575559.64

Authors

Zhou, Y.,Shamoo, Y. (deposition date: 2022-06-07, release date: 2023-07-05, Last modification date: 2023-11-15)

• Primary citation: Zhou, Y.,Shamoo, Y.; E. faecium MurAA in complex with fosfomycin and UNAG; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.65 Å)