8D6O

Nanorana parkeri saxiphilin:F-STX (soaked)

8D6O の概要

• エントリーDOI: 10.2210/pdb8d6o/pdb
• 分子名称: Saxiphilin, (2P)-4-({6-[({[(3aS,4R,7R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methoxy}carbonyl)amino]hexyl}carbamoyl)-2-{[4aP,9(9a)P]-6-hydroxy-3-oxo-3H-xanthen-9-yl}benzoic acid, PENTAETHYLENE GLYCOL, ... (4 entities in total)
• 機能のキーワード: saxiphilin, toxin resistance, saxitoxin, antitoxin
• 由来する生物種: Nanorana parkeri
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 95698.68

構造登録者

Zakrzewska, S.,Chen, Z.,Minor, D.L. (登録日: 2022-06-06, 公開日: 2022-11-02, 最終更新日: 2023-10-18)

• 主引用文献: Chen, Z.,Zakrzewska, S.,Hajare, H.S.,Alvarez-Buylla, A.,Abderemane-Ali, F.,Bogan, M.,Ramirez, D.,O'Connell, L.A.,Du Bois, J.,Minor Jr., D.L.; Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.; Proc.Natl.Acad.Sci.USA, 119:e2210114119-e2210114119, 2022; PubMed: 36279441; DOI: 10.1073/pnas.2210114119

実験手法

X-RAY DIFFRACTION (2.2 Å)