8D4Y

C-terminal SANT-SLIDE domain of human Chromodomain-helicase-DNA-binding protein 4 (CHD4)

Summary for 8D4Y

• Entry DOI: 10.2210/pdb8d4y/pdb
• Descriptor: Chromodomain-helicase-DNA-binding protein 4 (2 entities in total)
• Functional Keywords: chromodomain, sant, slide, nurd, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 98535.06

Authors

Moghaddas Sani, H.,Deshpande, C.N.,Panjikar, S.,Patel, K.,Mackay, J.P. (deposition date: 2022-06-03, release date: 2022-12-21, Last modification date: 2024-04-03)

• Primary citation: Zhong, Y.,Moghaddas Sani, H.,Paudel, B.P.,Low, J.K.K.,Silva, A.P.G.,Mueller, S.,Deshpande, C.,Panjikar, S.,Reid, X.J.,Bedward, M.J.,van Oijen, A.M.,Mackay, J.P.; The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families.; Nat Commun, 13:7524-7524, 2022; PubMed: 36473839; DOI: 10.1038/s41467-022-35002-0

Experimental method

X-RAY DIFFRACTION (2.9 Å)