8D4U

Crystal Structure of Neutrophil Elastase Inhibited by Eap2 from S. aureus

8D4U の概要

• エントリーDOI: 10.2210/pdb8d4u/pdb
• 関連するPDBエントリー: 8D4Q 8D4S
• 分子名称: Neutrophil elastase, Extracellular Adherence Protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: protease inhibitor, immune evasion, neutrophil, s. aureus, protein binding, hydrolase-inhibitor, protein binding complex, hydrolase/inhibitor
• 由来する生物種: Staphylococcus aureus subsp. aureus; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 70047.09

構造登録者

Gido, C.D.,Herdendorf, T.J.,Geisbrecht, B.V. (登録日: 2022-06-02, 公開日: 2022-12-21, 最終更新日: 2023-10-25)

• 主引用文献: Gido, C.D.,Herdendorf, T.J.,Geisbrecht, B.V.; Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family.; J.Biol.Chem., 299:102969-102969, 2023; PubMed: 36736422; DOI: 10.1016/j.jbc.2023.102969

実験手法

X-RAY DIFFRACTION (1.9 Å)