8D3H
Crystal structure of human Apoptosis-Inducing Factor (AIF) W196A mutant complexed with 7-chloroquinolin-4-amine
Summary for 8D3H
Entry DOI | 10.2210/pdb8d3h/pdb |
Descriptor | Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, 7-chloroquinolin-4-amine, ... (6 entities in total) |
Functional Keywords | oxidoreductase, mitochondrial import, oxidative phosphorylation, saxs |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 120749.27 |
Authors | |
Primary citation | Brosey, C.A.,Link, T.,Shen, R.,Moiani, D.,Burnett, K.,Hura, G.,Jones, D.E.,Tainer, J.A. Integrating early structural selection into chemical library screening for drug discovery with high-throughput small-angle X-ray scattering (SAXS) To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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