8D29

Crystal structure of theophylline aptamer - apo form

Summary for 8D29

• Entry DOI: 10.2210/pdb8d29/pdb
• Descriptor: Fab heavy chain, Fab light chain, RNA (34-MER), ... (6 entities in total)
• Functional Keywords: rna, aptamer, theophylline, rna-immune system complex, rna/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 234612.82

Authors

Menichelli, E.,Spraggon, G. (deposition date: 2022-05-28, release date: 2022-11-30, Last modification date: 2023-10-25)

• Primary citation: Menichelli, E.,Lam, B.J.,Wang, Y.,Wang, V.S.,Shaffer, J.,Tjhung, K.F.,Bursulaya, B.,Nguyen, T.N.,Vo, T.,Alper, P.B.,McAllister, C.S.,Jones, D.H.,Spraggon, G.,Michellys, P.Y.,Joslin, J.,Joyce, G.F.,Rogers, J.; Discovery of small molecules that target a tertiary-structured RNA.; Proc.Natl.Acad.Sci.USA, 119:e2213117119-e2213117119, 2022; PubMed: 36413497; DOI: 10.1073/pnas.2213117119

Experimental method

X-RAY DIFFRACTION (1.81 Å)