8D24
Crystal structure of Plasmodium falciparum GRP78-NBD in complex with VER155008
Summary for 8D24
Entry DOI | 10.2210/pdb8d24/pdb |
Descriptor | Chaperone DnaK, 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, SULFATE ION, ... (4 entities in total) |
Functional Keywords | atpase, chaperone |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 1 |
Total formula weight | 45108.91 |
Authors | Mrozek, A.,Park, H.W. (deposition date: 2022-05-27, release date: 2023-05-31, Last modification date: 2023-12-13) |
Primary citation | Mrozek, A.,Antoshchenko, T.,Chen, Y.,Zepeda-Velazquez, C.,Smil, D.,Kumar, N.,Lu, H.,Park, H.W. A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues. Front Mol Biosci, 9:956095-956095, 2022 Cited by PubMed: 36275624DOI: 10.3389/fmolb.2022.956095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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