8CYY

CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V

Summary for 8CYY

• Entry DOI: 10.2210/pdb8cyy/pdb
• EMDB information: 27082 27083 27084 27085 27086 27087 27088 27089 27090 27091 27092 27093
• Descriptor: Alpha-synuclein (1 entity in total)
• Functional Keywords: alpha-synuclein, cerebrospinal fluid (csf), dlb, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 173713.30

Authors

Zhou, Y.,Sokratian, A.,Xu, E.,Viverette, E.,Dillard, L.,Yuan, Y.,Li, J.Y.,Matarangas, A.,Bouvette, J.,Borgnia, M.,Bartesaghi, A.,West, A. (deposition date: 2022-05-24, release date: 2023-05-31, Last modification date: 2024-06-12)

• Primary citation: Zhou, Y.,Sokratian, A.,Xu, E.,Viverette, E.,Dillard, L.,Yuan, Y.,Li, J.Y.,Matarangas, A.,Bouvette, J.,Borgnia, M.,Bartesaghi, A.,West, A.; Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)