8CVK

Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution

This is a non-PDB format compatible entry.

Summary for 8CVK

• Entry DOI: 10.2210/pdb8cvk/pdb
• Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (62 entities in total)
• Functional Keywords: 70s ribosome, non-hydrolyzable, aminoacyl-trna, peptidyl-trna, formylation, pre-attack state, transpeptidation, peptidyl transferase center, nascent peptide exit tunnel, ribosome, ribosome-rna complex, ribosome/rna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 114
• Total formula weight: 4570821.67

Authors

Syroegin, E.A.,Aleksandrova, E.V.,Polikanov, Y.S. (deposition date: 2022-05-18, release date: 2022-10-19, Last modification date: 2023-11-15)

• Primary citation: Syroegin, E.A.,Aleksandrova, E.V.,Polikanov, Y.S.; Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes.; Nat.Chem., 15:143-153, 2023; PubMed: 36316410; DOI: 10.1038/s41557-022-01073-1

Experimental method

X-RAY DIFFRACTION (2.5 Å)