8CV6
Peptide 4.2B in complex with BRD4.2
Summary for 8CV6
Entry DOI | 10.2210/pdb8cv6/pdb |
Descriptor | BRD4 protein, Peptide 4.2E, ACETYL GROUP, ... (5 entities in total) |
Functional Keywords | cyclic peptide inhibitor bromodomain, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 16351.91 |
Authors | Franck, C.,Mackay, J.P. (deposition date: 2022-05-18, release date: 2023-05-24, Last modification date: 2023-12-06) |
Primary citation | Franck, C.,Patel, K.,Walport, L.J.,Christie, M.,Norman, A.,Passioura, T.,Suga, H.,Payne, R.J.,Mackay, J.P. Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins. Structure, 31:912-923.e4, 2023 Cited by PubMed: 37269828DOI: 10.1016/j.str.2023.05.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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