8CPD
Cryo-EM structure of CRaf dimer with 14:3:3
Summary for 8CPD
Entry DOI | 10.2210/pdb8cpd/pdb |
Related | 8chf |
EMDB information | 16779 |
Descriptor | RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein zeta isoform X1 (2 entities in total) |
Functional Keywords | kinase, complex, cytokine |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 202585.98 |
Authors | Dedden, D.,Graedler, U.,Schwarz, D.,Thomsen, M.,Leuthner, B.,Schneider, E.,Nitsche, J. (deposition date: 2023-03-02, release date: 2024-02-21, Last modification date: 2024-02-28) |
Primary citation | Dedden, D.,Nitsche, J.,Schneider, E.V.,Thomsen, M.,Schwarz, D.,Leuthner, B.,Gradler, U. Cryo-EM Structures of CRAF 2 /14-3-3 2 and CRAF 2 /14-3-3 2 /MEK1 2 Complexes. J.Mol.Biol., 436:168483-168483, 2024 Cited by PubMed: 38331211DOI: 10.1016/j.jmb.2024.168483 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.46 Å) |
Structure validation
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