8CNF
Human Aldose Reductase Mutant L300G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)
8CNF の概要
エントリーDOI | 10.2210/pdb8cnf/pdb |
分子名称 | Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid, ... (5 entities in total) |
機能のキーワード | human aldose reductase, har, aldo-keto-reductase, mutant l300g, idd_06 ligand, nadp+, diabetes, ligand in transient pocket, no flip, oxidoreductase |
由来する生物種 | Homo sapiens (human) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 37126.05 |
構造登録者 | |
主引用文献 | Klee, L.-S.,Heine, A.,Klebe, G.,Scheer, F. Human Aldose Reductase Mutant L300G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) To Be Published, |
実験手法 | X-RAY DIFFRACTION (0.95 Å) |
構造検証レポート
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