8CM8

Galectin-8 N-terminal carbohydrate recognition domain in complex with 4-(bromophenyl)phthalazinone D-galactal ligand

Summary for 8CM8

• Entry DOI: 10.2210/pdb8cm8/pdb
• Descriptor: Galectin-8, 4-(4-bromophenyl)-2-[[(2~{R},3~{R},4~{R})-2-(hydroxymethyl)-3-oxidanyl-3,4-dihydro-2~{H}-pyran-4-yl]oxymethyl]phthalazin-1-one, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: galectin, phthalazinone, inhibitor, sugar binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 72662.14

Authors

Van Klaveren, S.,Hakansson, M.,Diehl, C.,Nilsson, N.J. (deposition date: 2023-02-17, release date: 2024-02-28)

• Primary citation: Van Klaveren, S.,Nilsson, N.J.; Halogenated Galactal-Phenylphthalazinone Hybrids as Highly Selective Galectin-8N Ligands; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.22 Å)