8CGY

Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing

8CGY の概要

• エントリーDOI: 10.2210/pdb8cgy/pdb
• 分子名称: Inosine-5'-monophosphate dehydrogenase, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: imp dehydrogenase, purine biosynthetic enzyme, native cofactors, transferase
• 由来する生物種: Trypanosoma brucei
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 113622.02

構造登録者

Boger, J.,Schoenherr, R.,Lahey-Rudolph, J.M.,Harms, M.,Kaiser, J.,Nachtschatt, S.,Wobbe, M.,Duden, R.,Bourenkov, G.,Schneider, T.,Redecke, L. (登録日: 2023-02-06, 公開日: 2024-02-21, 最終更新日: 2024-03-06)

• 主引用文献: Schonherr, R.,Boger, J.,Lahey-Rudolph, J.M.,Harms, M.,Kaiser, J.,Nachtschatt, S.,Wobbe, M.,Duden, R.,Konig, P.,Bourenkov, G.,Schneider, T.R.,Redecke, L.; A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst.; Nat Commun, 15:1709-1709, 2024; PubMed: 38402242; DOI: 10.1038/s41467-024-45985-7

実験手法

X-RAY DIFFRACTION (3 Å)