8CCY

Human heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium and 3'-phosphoadenosine-5'-phosphosulfate

Summary for 8CCY

• Entry DOI: 10.2210/pdb8ccy/pdb
• Related: 1NST
• EMDB information: 16564
• Descriptor: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, ADENOSINE-3'-5'-DIPHOSPHATE, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: deacetylase, sulfotransferase, heparan sulfate, carbohydrate, glycosaminoglycan
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 92914.82

Authors

Mycroft-West, C.J.,Wu, L. (deposition date: 2023-01-28, release date: 2024-02-07, Last modification date: 2024-02-28)

• Primary citation: Mycroft-West, C.J.,Abdelkarim, S.,Duyvesteyn, H.M.E.,Gandhi, N.S.,Skidmore, M.A.,Owens, R.J.,Wu, L.; Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1.; Nat Commun, 15:1326-1326, 2024; PubMed: 38351061; DOI: 10.1038/s41467-024-45419-4

Experimental method

ELECTRON MICROSCOPY (2.7 Å)