8CBE

SARS-CoV-2 Delta-RBD complexed with BA.4/5-2 and Beta-49 Fabs

Summary for 8CBE

• Entry DOI: 10.2210/pdb8cbe/pdb
• Related: 8CBD
• Descriptor: BA.4/5-2 heavy chain, BA.4/5-2 light chain, Spike protein S1, ... (6 entities in total)
• Functional Keywords: sars-cov-2, ba.4 mab, ba.5 mab, rbd, ba.4/5-1, ba.4/5-2, ba.4/5-5, beta-49, viral protein/immune system, viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 118413.27

Authors

Zhou, D.,Ren, J.,Stuart, D.I. (deposition date: 2023-01-25, release date: 2024-02-07, Last modification date: 2024-05-08)

• Primary citation: Liu, C.,Das, R.,Dijokaite-Guraliuc, A.,Zhou, D.,Mentzer, A.J.,Supasa, P.,Selvaraj, M.,Duyvesteyn, H.M.E.,Ritter, T.G.,Temperton, N.,Klenerman, P.,Dunachie, S.J.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection.; Nat Commun, 15:3284-3284, 2024; PubMed: 38627386; DOI: 10.1038/s41467-024-47393-3

Experimental method

X-RAY DIFFRACTION (3.16 Å)