8CA8
Crystal structure of SARS-CoV-2 Mpro-H172Y mutant, free enzyme
This is a non-PDB format compatible entry.
Summary for 8CA8
| Entry DOI | 10.2210/pdb8ca8/pdb |
| Descriptor | 3C-like proteinase nsp5, CHLORIDE ION (3 entities in total) |
| Functional Keywords | mpro mutations main protease sars-cov-2, antiviral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 |
| Total number of polymer chains | 1 |
| Total formula weight | 33410.49 |
| Authors | El Kilani, H.,Ibrahim, M.,Hilgenfeld, R. (deposition date: 2023-01-24, release date: 2024-08-07, Last modification date: 2025-09-03) |
| Primary citation | El Kilani, H.,Sun, X.,Ibrahim, M.F.,Curth, U.,Hilgenfeld, R. 13b-K and Nirmatrelvir Resistance Mutations of SARS-CoV-2 Main Protease: Structural, Biochemical, and Biophysical Characterization of Free Enzymes and Inhibitor Complexes Crystals, 15:-, 2025 Cited by DOI: 10.3390/cryst15090758PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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