8CA6

Crystal structure of SARS-CoV-2 Mpro-Q189K mutant, free enzyme

This is a non-PDB format compatible entry.

Summary for 8CA6

• Entry DOI: 10.2210/pdb8ca6/pdb
• Descriptor: Non-structural protein 11 (2 entities in total)
• Functional Keywords: mpro mutations main protease sars-cov-2, antiviral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 67653.20

Authors

El Kilani, H.,Hilgenfeld, R. (deposition date: 2023-01-24, release date: 2024-08-07, Last modification date: 2025-09-03)

• Primary citation: El Kilani, H.,Sun, X.,Ibrahim, M.F.,Curth, U.,Hilgenfeld, R.; 13b-K and Nirmatrelvir Resistance Mutations of SARS-CoV-2 Main Protease: Structural, Biochemical, and Biophysical Characterization of Free Enzymes and Inhibitor Complexes; Crystals, 15:-, 2025; DOI: 10.3390/cryst15090758

Experimental method

X-RAY DIFFRACTION (1.92 Å)