8C9F
Priestia megaterium inactive HIGH motif mutant of type1 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue.
Summary for 8C9F
Entry DOI | 10.2210/pdb8c9f/pdb |
Descriptor | Isoleucine--tRNA ligase, ZINC ION, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ... (7 entities in total) |
Functional Keywords | antibiotic, mupirocin-sensitive, ilers1, rna binding protein |
Biological source | Priestia megaterium |
Total number of polymer chains | 1 |
Total formula weight | 106993.21 |
Authors | Brkic, A.,Leibundgut, M.,Jablonska, J.,Zanki, V.,Car, Z.,Petrovic Perokovic, V.,Ban, N.,Gruic-Sovulj, I. (deposition date: 2023-01-21, release date: 2023-08-16, Last modification date: 2024-03-27) |
Primary citation | Brkic, A.,Leibundgut, M.,Jablonska, J.,Zanki, V.,Car, Z.,Petrovic Perokovic, V.,Marsavelski, A.,Ban, N.,Gruic-Sovulj, I. Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14:5498-5498, 2023 Cited by PubMed: 37679387DOI: 10.1038/s41467-023-41244-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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