8C8D

Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 44).

8C8D の概要

• エントリーDOI: 10.2210/pdb8c8d/pdb
• 分子名称: DNA cross-link repair 1A protein, (2~{R})-3-[6-chloranyl-2-(furan-2-ylmethylamino)quinazolin-4-yl]-2-methyl-~{N}-oxidanyl-propanamide, ZINC ION, ... (4 entities in total)
• 機能のキーワード: exonuclease, snm1a, nuclease inhibition, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39774.48

構造登録者

Yosaatmadja, Y.,Newman, J.A.,Baddock, H.T.,Bielinski, M.,von Delft, F.,Bountra, C.,McHugh, P.J.,Schofield, C.J.,Gileadi, O. (登録日: 2023-01-19, 公開日: 2024-01-31)

• 主引用文献: Yosaatmadja, Y.,Newman, J.A.,Baddock, H.T.,Bielinski, M.,von Delft, F.,Bountra, C.,McHugh, P.J.,Schofield, C.J.,Gileadi, O.; Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 44).; To Be Published,

実験手法

X-RAY DIFFRACTION (1.46 Å)