8C7W

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2304

8C7W の概要

• エントリーDOI: 10.2210/pdb8c7w/pdb
• 分子名称: Activin receptor type I, 6-methyl-9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,7-dihydropyrido[4,3-d][2]benzazepine, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: bmp signalling kinase inhibitor, signaling protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35918.91

構造登録者

Cros, J.,Williams, E.P.,Sweeney, M.N.,Smil, D.,Gonzalez-Alvarez, H.,Al-awar, R.,Bullock, A.N. (登録日: 2023-01-17, 公開日: 2023-02-08, 最終更新日: 2024-02-07)

• 主引用文献: Cros, J.,Williams, E.P.,Sweeney, M.N.,Smil, D.,Gonzalez-Alvarez, H.,Al-awar, R.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2304; To Be Published,

実験手法

X-RAY DIFFRACTION (2.26 Å)