8C6M
Human protein kinase CK2 alpha in complex with CK2-TN02
Summary for 8C6M
Entry DOI | 10.2210/pdb8c6m/pdb |
Related | 8C6L |
Descriptor | Casein kinase II subunit alpha, (5~{Z})-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazolidine-2,4-dione, SULFATE ION, ... (4 entities in total) |
Functional Keywords | kinase domain, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 40693.27 |
Authors | |
Primary citation | Cazzanelli, G.,Dalle Vedove, A.,Broso, F.,Burigotto, M.,Aiello, G.,Ruzzene, M.,Tiberi, L.,Fava, L.,Quattrone, A.,Lolli, G. Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma to be published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report