8C6L
Human protein kinase CK2 alpha in complex with CK2-TN01
Summary for 8C6L
Entry DOI | 10.2210/pdb8c6l/pdb |
Descriptor | Casein kinase II subunit alpha, 1,2-ETHANEDIOL, 5-azanyl-3-[(~{Z})-1-cyano-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]-3~{H}-pyrazole-4-carbonitrile, ... (5 entities in total) |
Functional Keywords | kinase domain, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 40785.35 |
Authors | |
Primary citation | Cazzanelli, G.,Dalle Vedove, A.,Broso, F.,Burigotto, M.,Aiello, G.,Ruzzene, M.,Tiberi, L.,Fava, L.,Quattrone, A.,Lolli, G. Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma to be published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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