8C5F

E. coli NfsB-T41Q/N71S/F124T mutant bound to acetate

8C5F の概要

• エントリーDOI: 10.2210/pdb8c5f/pdb
• 分子名称: Oxygen-insensitive NAD(P)H nitroreductase, FLAVIN MONONUCLEOTIDE, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: nitroreductase mutant, complex, oxidoreductase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49165.24

構造登録者

White, S.A.,Hyde, E.I.,Day, M.A. (登録日: 2023-01-07, 公開日: 2023-04-19, 最終更新日: 2024-06-19)

• 主引用文献: Day, M.A.,Christofferson, A.J.,Anderson, J.L.R.,Vass, S.O.,Evans, A.,Searle, P.F.,White, S.A.,Hyde, E.I.; Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.; Int J Mol Sci, 24:-, 2023; PubMed: 36983061; DOI: 10.3390/ijms24065987

実験手法

X-RAY DIFFRACTION (1.6 Å)