8C42

Ternary structure of 14-3-3sigma, PKA-responsive ERa phosphopeptide and Fusicoccin-A

Summary for 8C42

• Entry DOI: 10.2210/pdb8c42/pdb
• Descriptor: 14-3-3 protein sigma, Estrogen receptor, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: 14-3-3, hub-protein, era f-domain phosphopeptide, peptide binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 28195.55

Authors

Somsen, B.A.,Ottmann, C. (deposition date: 2022-12-30, release date: 2023-12-27, Last modification date: 2024-01-10)

• Primary citation: Somsen, B.A.,Sijbesma, E.,Leysen, S.,Honzejkova, K.,Visser, E.J.,Cossar, P.J.,Obsil, T.,Brunsveld, L.,Ottmann, C.; Molecular basis and dual ligand regulation of tetrameric estrogen receptor alpha /14-3-3 zeta protein complex.; J.Biol.Chem., 299:104855-104855, 2023; PubMed: 37224961; DOI: 10.1016/j.jbc.2023.104855

Experimental method

X-RAY DIFFRACTION (1.4 Å)