8C26

ParDE2 toxin-antitoxin complex from Mycobacterium tuberculosis (rv2142A-rv2142c)

8C26 の概要

• エントリーDOI: 10.2210/pdb8c26/pdb
• 分子名称: Toxin ParE2, Antitoxin ParD2, CHLORIDE ION (3 entities in total)
• 機能のキーワード: toxin-antitoxin gyrase inhibitor tuberculosis, toxin
• 由来する生物種: Mycobacterium tuberculosis H37Rv; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 20323.52

構造登録者

Beck, I.N.,Blower, T.R. (登録日: 2022-12-21, 公開日: 2023-12-20, 最終更新日: 2024-03-27)

• 主引用文献: Beck, I.N.,Arrowsmith, T.J.,Grobbelaar, M.J.,Bromley, E.H.C.,Marles-Wright, J.,Blower, T.R.; Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition.; Nucleic Acids Res., 52:1909-1929, 2024; PubMed: 38113275; DOI: 10.1093/nar/gkad1220

実験手法

X-RAY DIFFRACTION (2.35 Å)