8BZY

Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation

Summary for 8BZY

• Entry DOI: 10.2210/pdb8bzy/pdb
• EMDB information: 16345
• Descriptor: Solute carrier family 40 member 1, Sybody 3, DIUNDECYL PHOSPHATIDYL CHOLINE, ... (4 entities in total)
• Functional Keywords: iron, inhibitor, slc40, transporter, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 80911.21

Authors

Lehmann, E.F.,Liziczai, M.,Drozdzyk, K.,Dutzler, R.,Manatschal, C. (deposition date: 2022-12-15, release date: 2023-03-22, Last modification date: 2023-05-24)

• Primary citation: Lehmann, E.F.,Liziczai, M.,Drozdzyk, K.,Altermatt, P.,Langini, C.,Manolova, V.,Sundstrom, H.,Durrenberger, F.,Dutzler, R.,Manatschal, C.; Structures of ferroportin in complex with its specific inhibitor vamifeport.; Elife, 12:-, 2023; PubMed: 36943194; DOI: 10.7554/eLife.83053

Experimental method

ELECTRON MICROSCOPY (3.24 Å)