8BST
Crystal structure of the kainate receptor GluK3-H523A ligand binding domain in complex with kainate at 2.7A resolution
Summary for 8BST
Entry DOI | 10.2210/pdb8bst/pdb |
Descriptor | Glutamate receptor ionotropic, kainate 3, ACETATE ION, ZINC ION, ... (9 entities in total) |
Functional Keywords | ionotropic glutamate receptor, gluk3 ligand-binding domain, membrane protein, gluk3-m523a-lbd |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 4 |
Total formula weight | 119934.42 |
Authors | Venskutonyte, R.,Frydenvang, K.,Kastrup, J.S. (deposition date: 2022-11-26, release date: 2023-12-13, Last modification date: 2024-04-10) |
Primary citation | Bay, Y.,Venskutonyte, R.,Frantsen, S.M.,Thorsen, T.S.,Musgaard, M.,Frydenvang, K.,Francotte, P.,Pirotte, B.,Biggin, P.C.,Kristensen, A.S.,Boesen, T.,Pickering, D.S.,Gajhede, M.,Kastrup, J.S. Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. Febs J., 291:1506-1529, 2024 Cited by PubMed: 38145505DOI: 10.1111/febs.17046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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