8BSD

SARS-CoV-2 nsp10-16 methyltransferase in complex with tubercidin

8BSD の概要

• エントリーDOI: 10.2210/pdb8bsd/pdb
• 分子名称: 2'-O-methyltransferase nsp16, Non-structural protein 10, 1,2-ETHANEDIOL, ... (8 entities in total)
• 機能のキーワード: methyltransferase, complex, inhibitor, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51597.39

構造登録者

Kremling, V.,Oberthuer, D.,Sprenger, J. (登録日: 2022-11-24, 公開日: 2022-12-07, 最終更新日: 2024-11-13)

• 主引用文献: Kremling, V.,Falke, S.,Fernandez-Garcia, Y.,Ehrt, C.,Kiene, A.,Klopprogge, B.,Scheer, E.,Barthels, F.,Middendorf, P.,Kuhn, S.,Gunther, S.,Rarey, M.,Chapman, H.N.,Oberthur, D.,Sprenger, J.; SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug discovery; Elife, 2024; DOI: 10.7554/elife.98310.1

実験手法

X-RAY DIFFRACTION (1.95 Å)