8BR1

ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to Latrunculin-B-ATP-Mg-actin, and 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE and 2 Mg ions

Summary for 8BR1

Entry DOI	10.2210/pdb8br1/pdb
Related	7PJ0 7PSB 7Q9D
Descriptor	Actin, alpha skeletal muscle, intermediate form, Putative Adenylate cyclase, LATRUNCULIN B, ... (10 entities in total)
Functional Keywords	bacterial nucleotidyl cyclase toxin, activated complex, toxin
Biological source	Vibrio nigripulchritudo More
Total number of polymer chains	4
Total formula weight	179472.00
Authors	Teixeira-Nunes, M.,Renault, L.,Retailleau, P. (deposition date: 2022-11-22, release date: 2023-09-20, Last modification date: 2023-10-04)
Primary citation	Teixeira-Nunes, M.,Retailleau, P.,Raoux-Barbot, D.,Comisso, M.,Missinou, A.A.,Velours, C.,Plancqueel, S.,Ladant, D.,Mechold, U.,Renault, L. Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19:e1011654-e1011654, 2023 Cited by PubMed: 37747912 DOI: 10.1371/journal.ppat.1011654 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.044 Å)

Structure validation