8BOW

X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with an inhibitor 617

8BOW の概要

• エントリーDOI: 10.2210/pdb8bow/pdb
• 分子名称: Glutamate carboxypeptidase 2, (2~{S})-2-[[(2~{S})-6-[[(2~{S})-3-naphthalen-2-yl-2-[[4-[[2-[(11~{Z})-4,7,10-tris(2-hydroxy-2-oxoethyl)-1,4,7,10-tetrazacyclododec-11-en-1-yl]ethanoylamino]methyl]cyclohexyl]carbonylamino]propanoyl]amino]-1-oxidanyl-1-oxidanylidene-hexan-2-yl]carbamoylamino]pentanedioic acid, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen; inhibitor, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 84544.63

構造登録者

Motlova, L.,Barinka, C.,Benesova, M. (登録日: 2022-11-15, 公開日: 2023-11-29)

• 主引用文献: Motlova, L.,Barinka, C.,Benesova, M.; X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with an inhibitor 617; To Be Published,

実験手法

X-RAY DIFFRACTION (1.58 Å)