8BK5

A structure of the truncated LpMIP with bound inhibitor JK095.

Summary for 8BK5

Entry DOI	10.2210/pdb8bk5/pdb
Descriptor	Peptidyl-prolyl cis-trans isomerase, (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-(hydroxymethyl)-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one, SODIUM ION, ... (4 entities in total)
Functional Keywords	macrophage, potentiator, soluble, protein., structural protein
Biological source	Legionella pneumophila
Total number of polymer chains	1
Total formula weight	14899.74
Authors	Whittaker, J.J.,Guskov, A.,Goretzki, B.,Hellmich, U.A. (deposition date: 2022-11-08, release date: 2023-09-06, Last modification date: 2023-09-13)
Primary citation	Wiedemann, C.,Whittaker, J.J.,Perez Carrillo, V.H.,Goretzki, B.,Dajka, M.,Tebbe, F.,Harder, J.M.,Krajczy, P.R.,Joseph, B.,Hausch, F.,Guskov, A.,Hellmich, U.A. Legionella pneumophila macrophage infectivity potentiator protein appendage domains modulate protein dynamics and inhibitor binding. Int.J.Biol.Macromol., 252:126366-126366, 2023 Cited by PubMed: 37633566 DOI: 10.1016/j.ijbiomac.2023.126366 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.44 Å)

Structure validation