8BK4

Full length structure of the apo-state LpMIP.

Summary for 8BK4

• Entry DOI: 10.2210/pdb8bk4/pdb
• Descriptor: Macrophage infectivity potentiator, GLYCEROL, (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-(hydroxymethyl)-3-[(1~{S})-1-pyridin-2-ylethyl]-3,10-diazabicyclo[4.3.1]decan-2-one, ... (5 entities in total)
• Functional Keywords: macrophage, potentiator, soluble, protein., structural protein
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 1
• Total formula weight: 19158.34

Authors

Whittaker, J.J.,Guskov, A.,Goretzki, B.,Hellmich, U.A. (deposition date: 2022-11-08, release date: 2023-09-06, Last modification date: 2023-09-13)

• Primary citation: Wiedemann, C.,Whittaker, J.J.,Perez Carrillo, V.H.,Goretzki, B.,Dajka, M.,Tebbe, F.,Harder, J.M.,Krajczy, P.R.,Joseph, B.,Hausch, F.,Guskov, A.,Hellmich, U.A.; Legionella pneumophila macrophage infectivity potentiator protein appendage domains modulate protein dynamics and inhibitor binding.; Int.J.Biol.Macromol., 252:126366-126366, 2023; PubMed: 37633566; DOI: 10.1016/j.ijbiomac.2023.126366

Experimental method

X-RAY DIFFRACTION (1.34 Å)