8BK1
Mutant Imine Reductase IR007-143 from Amycolatopsis azurea, E120A, M197W, M206S, A213P, D238G, I240L
Summary for 8BK1
Entry DOI | 10.2210/pdb8bk1/pdb |
Descriptor | Mutant Imine Reductase IR007-143 from Amycolatopsis azurea, E120A, M197W, M206S, A213P, D238G, I240L, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | amine, imine nadph, biocatalyst, oxidoreductase |
Biological source | Amycolatopsis azurea |
Total number of polymer chains | 4 |
Total formula weight | 127394.46 |
Authors | |
Primary citation | Steflik, J.,Gilio, A.,Burns, M.,Grogan, G.,Kumar, R.,Lewis, R.,Martinez, C. Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor Acs Catalysis, 13:10065-10075, 2023 Cited by DOI: 10.1021/acscatal.3c01534PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)