8BJF

Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (inward-facing conformation)

Summary for 8BJF

• Entry DOI: 10.2210/pdb8bjf/pdb
• EMDB information: 16088
• Descriptor: ATP-binding cassette sub-family C member 4, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE (3 entities in total)
• Functional Keywords: abc transporter, abcc4, mrp4, translocase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 152414.13

Authors

Raj, I.,Bloch, M.,Pape, T.H.,Taylor, N.M.I. (deposition date: 2022-11-04, release date: 2023-08-30, Last modification date: 2023-11-15)

• Primary citation: Bloch, M.,Raj, I.,Pape, T.,Taylor, N.M.I.; Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4.; Structure, 31:1407-1418.e6, 2023; PubMed: 37683641; DOI: 10.1016/j.str.2023.08.014

Experimental method