8BJ5
Imine Reductase IR007 from Amycolatopsis azurea
Summary for 8BJ5
Entry DOI | 10.2210/pdb8bj5/pdb |
Descriptor | Imine Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | amine, imine nadph, biocatalyst, oxidoreductase |
Biological source | Amycolatopsis azurea |
Total number of polymer chains | 4 |
Total formula weight | 126942.52 |
Authors | |
Primary citation | Steflik, J.,Gilio, A.,Burns, M.,Grogan, G.,Kumar, R.,Lewis, R.,Martinez, C. Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor Acs Catalysis, 13:10065-10075, 2023 Cited by DOI: 10.1021/acscatal.3c01534PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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