8BIW

Cystathionine gamma-lyase N360S mutant in complex with DL-propargylglycine

8BIW の概要

• エントリーDOI: 10.2210/pdb8biw/pdb
• 分子名称: Cystathionine beta-lyase, putative, (2S)-2-aminopent-4-enoic acid, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: transsulfuration pathway, hydrogen sulfide, propargylglycine, toxoplasma, cytosolic protein
• 由来する生物種: Toxoplasma gondii
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92633.54

構造登録者

Fernandez-Rodriguez, C.,Conter, C.,Oyenarte, I.,Favretto, F.,Quintana, I.,Martinez-Chantar, M.L.,Astegno, A.,Martinez-Cruz, L.A. (登録日: 2022-11-02, 公開日: 2023-04-12, 最終更新日: 2024-02-07)

• 主引用文献: Fernandez-Rodriguez, C.,Conter, C.,Oyenarte, I.,Favretto, F.,Quintana, I.,Martinez-Chantar, M.L.,Astegno, A.,Martinez-Cruz, L.A.; Structural basis of the inhibition of cystathionine gamma-lyase from Toxoplasma gondii by propargylglycine and cysteine.; Protein Sci., 32:e4619-e4619, 2023; PubMed: 36883335; DOI: 10.1002/pro.4619

実験手法

X-RAY DIFFRACTION (1.981 Å)