8BF4

Crystal structure of Mouse Plexin-B1 (20-535) in complex with VHH15 and VHH14

Summary for 8BF4

• Entry DOI: 10.2210/pdb8bf4/pdb
• Descriptor: VHH14, Plexin-B1, VHH15, ... (7 entities in total)
• Functional Keywords: complex, inhibitor, vhh, nanobody, plexin, semaphorin, allosteric, signaling protein
• Biological source: Camelidae; More
• Total number of polymer chains: 6
• Total formula weight: 169950.42

Authors

Cowan, R.,Hall, G.,Carr, M. (deposition date: 2022-10-24, release date: 2023-05-03, Last modification date: 2023-09-20)

• Primary citation: Cowan, R.,Trokter, M.,Oleksy, A.,Fedorova, M.,Sawmynaden, K.,Worzfeld, T.,Offermanns, S.,Matthews, D.,Carr, M.D.,Hall, G.; Nanobody inhibitors of Plexin-B1 identify allostery in plexin-semaphorin interactions and signaling.; J.Biol.Chem., 299:104740-104740, 2023; PubMed: 37088134; DOI: 10.1016/j.jbc.2023.104740

Experimental method

X-RAY DIFFRACTION (2.15 Å)