8BD9

Crystal structure of TRIM33 alpha PHD-Bromo domain in complex with 10

Summary for 8BD9

• Entry DOI: 10.2210/pdb8bd9/pdb
• Related: 8BD8
• Descriptor: E3 ubiquitin-protein ligase TRIM33, 1,3-dimethylbenzimidazol-2-one, ZINC ION, ... (5 entities in total)
• Functional Keywords: trim33 alpha, phd-bromo domain, complex, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 24402.66

Authors

Tassone, G.,Pozzi, C.,Palomba, T. (deposition date: 2022-10-18, release date: 2022-12-07, Last modification date: 2024-01-31)

• Primary citation: Palomba, T.,Tassone, G.,Vacca, C.,Bartalucci, M.,Valeri, A.,Pozzi, C.,Cross, S.,Siragusa, L.,Desantis, J.; Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design.; Int J Mol Sci, 23:-, 2022; PubMed: 36430693; DOI: 10.3390/ijms232214218

Experimental method

X-RAY DIFFRACTION (3.2 Å)