8BCT

X-ray crystal structure of a de novo selected helix-loop-helix heterodimer in a syn arrangement, 26alpha/26beta

Summary for 8BCT

Entry DOI	10.2210/pdb8bct/pdb
Descriptor	26alpha, 26beta, SULFATE ION, ... (6 entities in total)
Functional Keywords	coiled coil, 4-helix bundle, in-cell library screening, protein-protein interactions, de novo protein
Biological source	synthetic construct More
Total number of polymer chains	8
Total formula weight	43534.53
Authors	Naudin, E.A.,Mylemans, B.,Smith, A.J.,Savery, N.J.,Woolfson, D.N. (deposition date: 2022-10-17, release date: 2023-06-07, Last modification date: 2024-05-01)
Primary citation	Smith, A.J.,Naudin, E.A.,Edgell, C.L.,Baker, E.G.,Mylemans, B.,FitzPatrick, L.,Herman, A.,Rice, H.M.,Andrews, D.M.,Tigue, N.,Woolfson, D.N.,Savery, N.J. Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology. Acs Synth Biol, 12:1845-1858, 2023 Cited by PubMed: 37224449 DOI: 10.1021/acssynbio.3c00231 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation