8BCS

X-ray crystal structure of a de novo designed helix-loop-helix homodimer in an anti arrangement, CC-HP1.0

Summary for 8BCS

Entry DOI	10.2210/pdb8bcs/pdb
Descriptor	CC-HP1.0, ACETATE ION (2 entities in total)
Functional Keywords	coiled coil, 4-helix bundle, de novo protein design, helix-loop-helix dimer, de novo protein
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	5334.31
Authors	Edgell, C.L.,Mylemans, B.,Naudin, E.A.,Smith, A.J.,Savery, N.J.,Woolfson, D.N. (deposition date: 2022-10-17, release date: 2023-06-07, Last modification date: 2024-02-07)
Primary citation	Smith, A.J.,Naudin, E.A.,Edgell, C.L.,Baker, E.G.,Mylemans, B.,FitzPatrick, L.,Herman, A.,Rice, H.M.,Andrews, D.M.,Tigue, N.,Woolfson, D.N.,Savery, N.J. Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology. Acs Synth Biol, 12:1845-1858, 2023 Cited by PubMed: 37224449 DOI: 10.1021/acssynbio.3c00231 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation