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8BBH

The crystal structure of a mouse Fab fragment TL1 in complex with a human Glucose-6-phosphate isomerase peptide 293-307

Summary for 8BBH
Entry DOI10.2210/pdb8bbh/pdb
DescriptorGlucose-6-phosphate isomerase, Heavy Chain of TL1 Fab fragment, Light Chain of TL1 Fab fragment, ... (4 entities in total)
Functional Keywordsantibody fab fragment, immune system
Biological sourceMus musculus
More
Total number of polymer chains3
Total formula weight48744.60
Authors
Ge, C.,Holmdahl, R.,Li, T. (deposition date: 2022-10-13, release date: 2022-12-21, Last modification date: 2023-07-05)
Primary citationLi, T.,Ge, C.,Kramer, A.,Sareila, O.,Leu Agelii, M.,Johansson, L.,Forslind, K.,Lonnblom, E.,Yang, M.,Xu, B.,Li, Q.,Cheng, L.,Bergstrom, G.,Fernandez, G.,Kastbom, A.,Rantapaa-Dahlqvist, S.,Gjertsson, I.,Holmdahl, R.
Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage.
Ann Rheum Dis, 82:799-808, 2023
Cited by
PubMed: 36858822
DOI: 10.1136/ard-2022-223633
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.619 Å)
Structure validation

221051

數據於2024-06-12公開中

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