8BA5

Crystal structure of the DNMT3A ADD domain

Summary for 8BA5

• Entry DOI: 10.2210/pdb8ba5/pdb
• Descriptor: DNA (cytosine-5)-methyltransferase 3A, 1,2-ETHANEDIOL, ZINC ION, ... (5 entities in total)
• Functional Keywords: methyltransferase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 16656.37

Authors

Linhard, V.,Kunert, S.,Wollenhaupt, J.,Broehm, A.,Schwalbe, H.,Jeltsch, A. (deposition date: 2022-10-11, release date: 2022-11-23, Last modification date: 2024-02-07)

• Primary citation: Kunert, S.,Linhard, V.,Weirich, S.,Choudalakis, M.,Osswald, F.,Kramer, L.,Kohler, A.R.,Brohm, A.,Wollenhaupt, J.,Schwalbe, H.,Jeltsch, A.; The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site.; Protein Sci., 32:e4542-e4542, 2023; PubMed: 36519786; DOI: 10.1002/pro.4542

Experimental method

X-RAY DIFFRACTION (1.45 Å)