8BA5
Crystal structure of the DNMT3A ADD domain
Summary for 8BA5
Entry DOI | 10.2210/pdb8ba5/pdb |
Descriptor | DNA (cytosine-5)-methyltransferase 3A, 1,2-ETHANEDIOL, ZINC ION, ... (5 entities in total) |
Functional Keywords | methyltransferase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 16656.37 |
Authors | Linhard, V.,Kunert, S.,Wollenhaupt, J.,Broehm, A.,Schwalbe, H.,Jeltsch, A. (deposition date: 2022-10-11, release date: 2022-11-23, Last modification date: 2024-02-07) |
Primary citation | Kunert, S.,Linhard, V.,Weirich, S.,Choudalakis, M.,Osswald, F.,Kramer, L.,Kohler, A.R.,Brohm, A.,Wollenhaupt, J.,Schwalbe, H.,Jeltsch, A. The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site. Protein Sci., 32:e4542-e4542, 2023 Cited by PubMed: 36519786DOI: 10.1002/pro.4542 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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