8B9I

Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA

Summary for 8B9I

• Entry DOI: 10.2210/pdb8b9i/pdb
• EMDB information: 15932
• Descriptor: Dosage compensation regulator, RNA (5'-R(P*CP*CP*UP*CP*UP*UP*UP*CP*UP*UP*U)-3'), ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: rna helicase, drosophila dosage compensation, rna binding protein
• Biological source: Drosophila melanogaster (fruit fly); More
• Total number of polymer chains: 2
• Total formula weight: 134643.66

Authors

Jagtap, P.K.A.,Hennig, J. (deposition date: 2022-10-06, release date: 2023-10-18, Last modification date: 2024-05-01)

• Primary citation: Jagtap, P.K.A.,Muller, M.,Kiss, A.E.,Thomae, A.W.,Lapouge, K.,Beck, M.,Becker, P.B.,Hennig, J.; Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.; Mol.Cell, 83:4318-4333.e10, 2023; PubMed: 37989319; DOI: 10.1016/j.molcel.2023.10.026

Experimental method

ELECTRON MICROSCOPY (2.95 Å)