8B77
The crystal structure of N828V variant of DNA Pol Epsilon containing dATP in the polymerase active site
Summary for 8B77
| Entry DOI | 10.2210/pdb8b77/pdb |
| Descriptor | DNA polymerase epsilon catalytic subunit A, Primer DNA sequence, Template DNA sequence, ... (5 entities in total) |
| Functional Keywords | protein-dna complex, n828v, ribonucleotide, dna binding protein |
| Biological source | Saccharomyces cerevisiae (baker's yeast) More |
| Total number of polymer chains | 3 |
| Total formula weight | 145772.21 |
| Authors | Parkash, V.,Johansson, E. (deposition date: 2022-09-29, release date: 2023-10-25, Last modification date: 2023-11-01) |
| Primary citation | Parkash, V.,Kulkarni, Y.,Bylund, G.O.,Osterman, P.,Kamerlin, S.C.L.,Johansson, E. A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023 Cited by PubMed: 37819038DOI: 10.1093/nar/gkad817 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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