8B53

Structure of porcine pancreatic elastase bound to a fragment of a 4-azaindole inhibitor

Summary for 8B53

• Entry DOI: 10.2210/pdb8b53/pdb
• Descriptor: Chymotrypsin-like elastase family member 1, 3-methylbenzoic acid, SULFATE ION, ... (6 entities in total)
• Functional Keywords: elastase, serine protease, hydrolase
• Biological source: Sus scrofa (pig)
• Total number of polymer chains: 1
• Total formula weight: 29209.78

Authors

Ferraroni, M.,Gerace, A. (deposition date: 2022-09-21, release date: 2023-09-20)

• Primary citation: Gerace, A.,Masini, V.,Crocetti, L.,Giovannoni, M.P.,Ferraroni, M.; X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones; J.Mol.Struct., 1274:134595-, 2023; DOI: 10.1016/j.molstruc.2022.134595

Experimental method

X-RAY DIFFRACTION (1.25 Å)