8B50

Crystal structure of a Fab fragment in complex with L-hydroxycoumarylalanine

8B50 の概要

• エントリーDOI: 10.2210/pdb8b50/pdb
• 分子名称: Fab fragment K12F9-22 - heavy chain, Fab fragment K12F9-22 - light chain, (2~{S})-2-azanyl-3-(7-oxidanyl-2-oxidanylidene-chromen-4-yl)propanoic acid, ... (5 entities in total)
• 機能のキーワード: antibody, fluorescent side chain, hapten, non-natural amino acid, recombinant fab, umbelliferylalanine, immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48882.70

構造登録者

Meining, W.,Eichinger, A.,Skerra, A. (登録日: 2022-09-21, 公開日: 2023-10-04, 最終更新日: 2026-03-04)

• 主引用文献: Rubini, M.,Meining, W.,Eichinger, A.,Mueller, M.,Kramer, K.,Skerra, A.; Preparation and characterization of monoclonal antibodies against a non natural amino acid carrying the 7-hydroxycoumarin side chain; To be published,

実験手法

X-RAY DIFFRACTION (1.67 Å)